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Table 1 Effect of acute cold exposure on BAT and cold-induced non-shivering thermogenesis

From: Brown fat thermogenesis and cold adaptation in humans

Participant

  

Condition

BAT activity

CIT (kcal/day)

  

Reference

N (M/F)

Age

BMI

  

Low BAT

High BAT

Difference

 

13 (13/0)

22.8

20.7

19 °C, light clothing, foot on ice, 2 h

- ~ + + + 

42

410

368

Yoneshiro et al. Obeisty 2011 (ref. [36])

27 (7/20)

40.2

22.8

17 °C, light clothing, 2 h

- ~ + + + 

167

287

120

Orava et al. Cell Metab 2011 (ref. [21])

6 (6/0)

23 to 42

23.7 to 31.0

19 °C cooling suit, 3 h

- ~ + + + + 

2002 (77% of EE), shivering

Ouellet et al. J Clin Invest 2012 (ref. [22])

51 (51/0)

24.4

22.0

19 °C, light clothing, 2 h

- ~ + + + 

78

252

174

Yoneshiro et al. J Clin Invest 2013 (ref. [44])

25 (10/15)

30.8

23.8

15.5 °C, light clothing, 2.5 h

- ~ + + + 

7

237

230

Muzik et al. J Nucl Med 2013 (ref. [25])

24 (14/10)

28.1

20 to 27

19 °C, 12 h

- ~ + + 

88 (5% of EE)

Chen et al. JCEM 2013 (ref. [40])

12 (12/0)

24

25.5

18 °C cooling suit, 3 h

- ~ + + + + 

1886 (82% of EE), shivering

Blondin et al. J Physiol 2015 (ref. [26])

15 (15/0)

22.2

22.7

14 °C cooling suit, 2 h

- ~ + + + 

128

Cypess et al. Cell Metab 2015 (ref. [24])

18 (18/0)

21.8

20.5

19 °C, light clothing, 2 h

- ~ + + + 

120

256

136

Wakabayashi et al. EJAP 2020 (ref. [41])

  1. -Undetectably low, + high